Development of a Plant-Based Hydrogel Using Bryophyllum pinnatum for Potential Wound-Healing Applications

Author

Sarvesh Diswah, Mr. Rahul, Mehak, Pooja, Suraj Prakash


Abstract

 Bryophyllum pinnatum is one of the important and most commonly used plant belongs to the family crassularaceae. Bryophyllum pinnatum commonly known as Patharchata. This plant is mainly used as a tropical medicinal plant in India, America and other countries. The physiochemical study shows presence of alkaloid, flavanoid, lipids, organic acids, phenols, triterpene, glycoside. It is widely used in treatment of haemostatic and wound healing. It is also used in treatment of CNS depressant, analgesic, anti-inflammatory, antidiabetic, anticonvulsant, anticancer, antiallergic, nephroprotective, hepatoprotective, antileishmanial, antiulcer activity Medicinal herbs have been utilised for centuries because they are safer, more effective, culturally acceptable, and have less adverse effects than manufactured medications. Therefore, I have focused my interest on making hydrogel from the medicinal plants bryophyllum pinnatum in the present review that have anti-inflammatory and analgesic property.


Keywords

Bryophyllum pinnatum, Plant-based hydrogel, Wound healing, Formulation & Characterization, Biological Activity



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References


  1. Rahul*Dr. Dev Prakash Dahiya International Journal of Research Publication and Reviews, Vol (6), Issue (9), September (2025), Page – 2479-2485.
  2. Rahul's, Subh Karan*, Dr. Dev Prakash Dahiya A Review of Phytoconstuents, Pharmacological Activity Along with Its Traditional and Medicinal Use of The Plant Ricinus Communis, Int. J. of Pharm. Sci., 2025, Vol 3, Issue 3, 2127-2133.
  3. Kamboj A, Saluja AK. Bryophyllum pinnatum (Lam.) Kurz.: Phytochemical and pharmacological profile: A review. Pharmacogn Rev. 2009;3(6):364–74.
  4. Thorat SS, Shah RR, Mohite SA, Patel NR. a Review on Bryophyllum Pinnatum. Int Res J Pharm. 2018;8(12):1–3.
  5. Afzal M, Kazmi I, Khan R, Singh R, Chauhan M, Bisht T, et al. Bryophyllum pinnatum : A review. Int J Res Biol Sci. 2012;2(4):143–9.
  6. Yadav S, Raut D, Nayak S. Antibacterial activity of Plectranthus Amboinicus against multiple drug-resistant isolates obtained from samples of urinary tract infection. Int J Bot Stud [Internet]. 2021;6(1):558–65. Available from: botanyjournals.com
  7. Thorat SS, Shah RR, Mohite SA, Patel NR. INTERNATIONAL RESEARCH JOURNAL OF PHARMACY.
  8. Afzal M, Kazmi I, Khan R, Singh R, Chauhan M, Bisht T, Anwar F. Bryophyllum pinnatum: a review. Int J Res Biol Sci. 2012;2(4):143-9.
  9. 4 Yadav S, Raut D, Nayak S. Antibacterial activity of Plectranthus Amboinicus against multiple drug-resistant isolates obtained from samples of urinary tract infection. CEP.;30(18):15-7.
  10. Idoko OD. EFFECTS OF HYDRO-METHANOL LEAF EXTRACT OF BRYOPHYLLUM PINNATUM ON DIAZEPAM-INDUCED SLEEPING TIME AND PENTYLENETETRAZOLE-INDUCED SEIZURE TEST IN MICE. Journal of Arts & Humanities. 2024;17(2)
  11. Selvakumar P. Phytochemical and pharmacological profile review of Bryophyllum pinnatum. Biomedical And Biotechnology Research Journal (Bbrj). 2022 Jul 1;6(3):295-301.(microscopic)
  12. Prasad AK, Kumar S, Iyer SV, Sudani RJ, Vaidya SK. Pharmacognostical, phytochemical and pharmacological review on Bryophyllum pinnata. International Journal of Pharmaceutical & Biological Archives. 2012 Oct 24;3(3):423-33.
  13. TOLARAM GM. EVALUATION OF THERAPEUTIC EFFICACY OF PLANTS Bryophyllum calycinum AND Achyranthes aspera ON ADENINE INDUCED CHRONIC KIDNEY DISEASE IN RATS.(.ijrp)
  14. Nagaratna A, Hegde PL. A comprehensive review on Parnabeeja [Bryophyllum pinnatum (Lam.) Oken]. Journal of medicinal plants studies. 2015;3(5):166-71.
  15. Elufioye TO, Oyedeji AO, Habtemariam S. A review of the traditional uses, phytochemistry and pharmacology of Bryophyllum pinnatum (Lam.)(Crassulaceae). Journal of Biologically Active Products from Nature. 2022 May 4;12(3):190-222.
  16. Supratman U, Fujita T, Akiyama K, Hayashi H. New insecticidal bufadienolide, bryophyllin C, from Kalanchoe pinnata. Bioscience, biotechnology, and biochemistry. 2000;64(6):1310-2.
  17. Singh S, Verma P, Verma P, Fatima K, Sharma S, Sharma A, Bhatt A, Sharma N, Barthwal J, Kumari P, Pant HC. A Review on In Vitro Culture Method and Assessment of Therapeutic potential of Bryophyllum pinnatum (Lam.).
  18. Arun Joseph UA, Kishore R, Harishankar RA, Sivakumar M, Deepa N. AN OVERVIEW OF THE PHYTOCHEMICAL AND PHARMACOLOGICAL EFFECTS OF BRYOPHYLLUM PINNATUM. Biochemical & Cellular Archives. 2023 Oct 1;23(2).
  19. Okwu DE, Uchenna NF. Exotic multifaceted medicinal plants of drugs and pharmaceutical industries. African Journal of Biotechnology. 2009;8(25).
  20. Singh RK, Garg A, Shrimali K. Botanical description, photochemistry, traditional uses, and pharmacology of the “wonder plant” Kalanchoe Pinnata (Linn.) Pers: an updated review. Journal of Pharmaceutical and Medicinal Chemistry. 2022 Jan;8(1).
  21. Menon N, Sparks J, Omoruyi F. Hypoglycemic and hypocholesterolemic activities of the aqueous preparation of Kalanchoe pinnata leaves in streptozotocin-induced diabetic rats. Asian Pacific Journal of Tropical Biomedicine. 2015 Jan 1;5(1):3-9.
  22. Yadav M, Gulkari VD, Wanjari MM. Bryophyllum pinnatum leaf extracts prevent formation of renal calculi in lithiatic rats. Ancient science of life. 2016 Oct 1;36(2):90-7.

 

 

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