COMPARATIVE STUDY OF EFFICACY OF THYROIDINUM 3X VS INDIVIDUALIZED HOMOEOPATHIC MEDICINE IN IMPROVING QUALITY OF LIFE IN PATIENTS WITH PRIMARY HYPOTHYROIDISM

Author

Dr. Leepika


Abstract

 Background: Primary hypothyroidism is associated with a range of physical, emotional and social manifestations that may affect quality of life. This study compared Thyroidinum 3X with individualized homoeopathic medicine in patients with primary hypothyroidism.

Objective: To compare the efficacy of Thyroidinum 3X and individualized homoeopathic medicine in improving quality of life in patients suffering from primary hypothyroidism, and to compare their effects on thyroid function tests.

Methods: An experimental comparative study was conducted on 30 patients with primary hypothyroidism, aged 20–45 years. Fifteen patients received individualized homoeopathic medicine and fifteen received Thyroidinum 3X. Patients were assessed clinically and by the SF-36 questionnaire, with thyroid function tests including TSH, T3 and T4. Follow-up was carried out every 15 days and as required. Statistical analysis was performed using the Mann–Whitney U test after assessment of normality by the Shapiro–Wilk test.

Results: In the individualized homoeopathic medicine group, 11 of 15 patients (73.33%) showed improvement in quality of life according to the reported SF-36 assessment, compared with 6 of 15 patients (40%) in the Thyroidinum 3X group. The study also reported greater reduction in TSH levels in the individualized homoeopathic medicine group.

Conclusion: Within the study data reported, individualized homoeopathic medicine showed greater improvement in the reported quality-of-life and TSH outcomes than Thyroidinum 3X.



Keywords

Primary hypothyroidism; Thyroidinum 3X; individualized homoeopathic medicine; quality of life; SF-36; TSH



Full Text:

Download Paper PDF


References


  1. Harrison’s Manual of Medicine.
  2. Unisa S. [Reference listed in the source bibliography, 1999].
  3. Zargar AH. [Reference listed in the source bibliography, 1997].
  4. Priya et al. [Reference listed in the source bibliography, 2015].
  5. Assessment of iodine deficiency disorders and monitoring their elimination. A guide for programme managers. 3rd ed. Geneva: World Health Organization; 2007.
  6. Carle A, Pedersen IB, Knudsen N, Perrild H, Ovesen L, Laurberg P. Gender differences in symptoms of hypothyroidism: a population-based DanThyr study. Clin Endocrinol. 2015;83:717–725.
  7. Carle A, Pedersen IB, Knudsen N, et al. Hypothyroid symptoms fail to predict thyroid insufficiency in old people: a population-based case-control study. Am J Med. 2016;129:1082–1092.
  8. Gao X, Liu M, Qu A, et al. Native magnetic resonance T1-mapping identifies diffuse myocardial injury in hypothyroidism. PLoS One. 2016;11:e0151266.
  9. Tiller D, Ittermann T, Greiser KH, et al. Association of serum thyrotropin with anthropometric markers of obesity in the general population. Thyroid. 2016;26:1205–1214.
  10. Huang SA, Tu HM, Harney JW, et al. Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med. 2000;343:185–189.
  11. Beynon J, Akhtar S, Kearney T. Predictors of outcome in myxoedema coma. Crit Care. 2008;12:111.
  12. Feldt-Rasmussen U, Effraimidis G, Klose M. The hypothalamus-pituitary-thyroid axis and its role in physiology and pathophysiology of other hypothalamic-pituitary functions. Mol Cell Endocrinol. 2021;525:111173.

Share your valuable work from Social Media Buttons