Development and Evaluation of a Transfersomal Loaded Herbal Dual Action Serum Containing Hibiscus and Green Tea Extract for Anti Aging and Skin Brightening Therapy

Author

Rubicashree S, Chaya P, Srinidhi C, Murali R, Anju K.P

Abstract

 The growing demand for multifunctional, plant-based cosmeceuticals has driven the exploration of advanced drug delivery systems that enhance efficacy and safety. This review focuses on a dual-functional approach employing herbal transferosomal-loaded serum for simultaneous anti-aging and skin brightening therapy using Hibiscus rosa-sinensis and Camellia sinensis (green tea) extracts as bioactive agents. 

Despite their therapeutic potential, the clinical application of these phytoconstituents is limited by poor skin penetration and stability. Transferosomes, ultra-deformable vesicular carriers, offer a promising solution by enhancing transdermal delivery, improving bioavailability, and enabling targeted release of active compounds into deeper skin layers. This review systematically discusses the formulation strategies, physicochemical characterization, and evaluation parameters of transferosomal systems incorporated into serum-based topical formulations. Additionally, it highlights the synergistic benefits of combining anti-aging and skin brightening activities in a single nano herbal transferosomal serum formulation.

Keywords

Tranferosomal serum, ethanol injection method, Hibiscus rosa-sinensis, Camellia sinensis, anti-aging, skin brightening serum.

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References

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