FORMULATION AND EVALUATION OF HYDROGEL BEAD SERUM FOR SKIN HYDRATION AND ACNE TREATMENT

Author

Rahul P, Rathinam A, Rathinapriya M, Revathi S, Mr. S. Mohan Kumar, Dr. J. Karthi, Dr. S. Swarnalatha


Abstract

 Acne vulgaris is a chronic inflammatory disease of the sebaceous follicles that requires long-term treatment with topical drugs, the frequent use of which leads to various side effects, including dermatitis and xerosis of the skin. The purpose of this study was to develop and investigate a serum containing niacinamide and hyaluronic acid in the form of hydrogel beads for prolonged release of the active ingredients and improved moisturizing properties. The hydrogel beads were obtained by ionotropic gelation of sodium alginate using calcium chloride solution as a crosslinking agent according to the egg-box mechanism.



Keywords

Hydrogel beads, niacinamide, hyaluronic acid, ionotropic gelation, sodium alginate, acne vulgaris, controlled release.



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